Symptoms, Causes and Homeopathy Treatment of Hailey Hailey Disease
The Hailey-Hailey disease is also referred to as familial benign chronic pemphigus. It is indeed a rare inherited skin condition, in which red, scaly areas or small blisters do appear at sites of friction. The condition tends to get worse with sweating as well as friction and in hot weather.
Causes of Hailey Hailey Disease:
The disease is inherited and there is a 1 in 2 chance that is 50 to 50 chance that each of the children of an affected parent will inherit this skin problem.
Hailey-Hailey disease as mentioned is due to genetic change (mutation) in the ATP2C1gene. The ATP2C1 gene does contain instructions for creating (encoding) a protein that acts as a calcium and magnesium pump in the cells. This protein does pump calcium or magnesium ions into a specialized organelle in the cell known as the Golgi apparatus. Calcium ions do play an essential role in cell-to-cell adhesion and, when the calcium pump does not function properly, the affected cells will not actually stick together, thus damaging the skin (acantholysis). The exact process by which loss or improper function of this protein product of the ATP2C1 gene does indeed cause Hailey-Hailey disease is not fully understood. The protein is most active in keratinocytes, the main cell type of the outermost layer of skin (epidermis). Failure of the keratinocytes to stick together does result in blisters.
Symptoms of Hailey Hailey Disease:
This disease is indeed a nuisance and the affected skin is itchy as well as uncomfortable and the patches do come as well as go. The affected skin is rather uncomfortable in case the skin surfaces are continually rubbing e.g the groins when walking. Very rarely actually the severe flare-up in the groins, genital area or the crease of one’s buttocks may actually make walking difficult and also work very uncomfortable.
The initial signs of this heat condition do usually appear between the ages of 15 as well as 40 years but can also begin outside this age range.
The severity varies quite enormously and is rather unpredictable. There will be red, scaly areas or small blisters that appear at various areas of breasts, especially on the sides of one’s neck or even in one’s skin folds under one’s arms, at the top of one’s legs or even under the breasts. The skin does appear to be entirely normal in between active episodes and does not result in any scar. Many patients do notice that the condition does improve as they grow older. It is often mistaken for eczema ( or dermatitis) and is sweat rash ringworm or impetigo which happens to be a bacterial skin infection. The diagnosis can be made with the help of a microscope by examining the affected skin area.
Treatment for Hailey Hailey Disease
It is evident that the underlying genetic defect cannot be altered. At the same time, treatment does help and log remissions are quite common.
Homeopathy Treatment of Hailey Hailey Disease
This is a very beneficial form of treatment. This condition at times becomes resistance to the conventional treatment of local steroids as well as physicians do often resort to oral steroids in order to control the flare-ups. Homeopathy treatment in Hyderabad reduces the intensity as well as the frequency of the flare-up and also helps in leading a comfortable life. It helps in reducing the dependency on steroids and also helps reduce the itching, redness as well inflammation, it does help in ensuring the overall long term management of the condition. One can be ensured bout safe medicines.
There are no comments